The Hotel Rheinfelderhof is located in the direct vicinity of Messe Basel and the Kongresszentrum. It is only 5 minutes on foot to Basel city centre with its many cultural highlights. The tram stop is in the immediate vicinity of the hotel.

The EuroAirport Basel Mulhouse is only 15 minutes away by car. Basel SBB railway station is only 7 minutes away from the hotel. The Badischer Bahnhof railway station is also only 3 minutes away from the hotel.